With the ability to replicate in human airway cultures, produce in vivo pathogenesis, and escape current therapeutics, SHC014 chimeric viruses illustrate the need for both surveillance and improved therapeutics against circulating SARS-like viruses.
https://www.nature.com/articles/s41591-020-0820-9 https://www.nature.com/articles/s41591-020-0820-9 SARS-CoV-2 may bind human ACE2 with high affinity, computational analyses predict that the interaction is not ideal7 and that the RBD sequence is different from those shown in SARS-CoV to be optimal for receptor binding7,11. Thus, the high-affinity binding of the SARS-CoV-2 spike protein to human ACE2 is most likely the result of natural selection on a human or human-like ACE2 that permits another optimal binding solution to arise. This is strong evidence that SARS-CoV-2 is not the product of purposeful manipulation. ------------------------------------ 人工改的不夠完美,就是自然演化嗎?
https://youtu.be/uAaDC0lv13s https://youtu.be/uAaDC0lv13s Taiwan's aggressive efforts are paying off in fight against COVID-19 台灣捐1000萬片口罩給疫情嚴重國家, 捐200萬片口罩給美國US